Cosimo Trono
Cosimo Trono graduated in Physics from the University of Florence in 10 October 1998, and obtained the PhD from the University of Florence in 14 July 2003. Since 1998 he joined the Fibre Optics Group at the Institute of Electromagnetic Wave of CNR in Florence (now named Institute of Applied Physics “Nello Carrara”), with temporary contracts.
His research activity was devoted to the design and development of optical sensors and to the study of novel optical methods for sensing. He has been actively involved in several measurement campaigns, designing and developing the Bragg grating based probes and contributing to the plan of the measurement methodology. Examples of that are application to the cultural heritage with a monitoring campaign of wooden works of art, application to building and wide structures, applications to mechanical engineering with the measurement of deformation of critical components of vehicles. He actively collaborated with Pisa University in the design of static and dynamic pressure sensors based on single mode fibre laser, developing in the CNR-IFAC laboratories the technique for the realization of single mode erbium doped fibre lasers. Recently he has become active in the field of optical sensors for chemical and biochemical parameters with applications to the biomedical field, and in the field of the microfluidic device development and their integration into detection optoelectronic devices.
He has been the prominent actor in the following research lines: design and development of a fibre optics based sensor for the monitoring of the illumination into the museum environment (the sensor was patented in Italy, Europe and USA); design and development a workstation for the realization and characterization of fiber Bragg gratings (FBGs), long period gratings (LPGs) and fiber lasers for sensing applications; design and development of a prototype of thermostatized fluidic system for LPG based assay development; design and development of a Point of Care instrument for the detection of biochemical parameters of clinical interest; design and development of an optoelectronic workstation for conventional fluorescence detection and for time-resolved lifetime fluorescence detection. He is holder of international patents and author of more than forty publications in International Journals and in International Conference Proceedings.
Publications List
Patents
US patent US9772292 B2, F. Baldini, C. Trono, “Fiber optic probe and measuring sensor using said probe”, Grant of the patent 26/09/2017, Registration 30/11/2011.
US patent US6567158 B1, A.G. Mignani, R. Falciai, C. Trono: “Fiber optic sensor with photochromic transducer, and corresponding method”, Grant of the patent 20/05/03.
International Journals
D. Di Minno, C. Trono, L. Capineri, A. Blundo, G. Masotti, Experimental Evaluation of Different Optical Fibers for Micro-Invasive Soft-Tissue Ablation with a 1064 nm Diode Laser System, Sensors (2026), 26 (3), doi:10.3390/s26031073
G. Frigenti, N. Marcucci, F. Baldini, C. Trono*, Multiplexed detection using two serial long period gratings in a Mach-Zehnder interferometer configuration, Optics and Laser Technology (2026), 193 , doi:10.1016/j.optlastec.2025.114129
M. Fytory, A. Giannetti, F. Baldini, S. Berneschi, N. Marcucci, C. Trono, S. Tombelli, Glass-based microfluidics in biosensing and bioassays: from fabrication techniques to application to bacteria detection, Optical Materials (2025), 167, doi:10.1016/j.optmat.2025.117350
C. Trono, Long period fiber grating-based biosensing: Recent trends and future perspectives, TrAC - Trends in Analytical Chemistry (2024), 179, doi:10.1016/j.trac.2024.117875
M. Banchelli, S. Tombelli, M. de Angelis, C. D’Andrea, C. Trono, F. Baldini, A. Giannetti, P. Matteini, Molecular beacon decorated silver nanowires for quantitative miRNA detection by a SERS approach, Analytical Methods (2023), 15 (45), 6165 - 6176, doi:10.1039/d3ay01661g
T. K. Dey, C. Trono*, P. Biswas, A. Giannetti, N. Basumallick, F. Baldini, S. Bandyopadhyay, S. Tombelli, Biosensing by Polymer-Coated Etched Long-Period Fiber Gratings Working near Mode Transition and Turn-around Point, Biosensors (2023), 13 (7), doi:10.3390/bios13070731
T. K. Dey, S. Tombelli, A. Roy, P. Biswas, A. Giannetti, N. Basumallick, F. Baldini, S. Bandyopadhyay, C. Trono*, Sensitivity Analysis of Sidelobes of the Lowest Order Cladding Mode of Long Period Fiber Gratings at Turn Around Point, Sensors (2022), 22 (8), doi:10.3390/s22082965
S. Tombelli, C. Trono*, S. Berneschi, C. Berrettoni, A. Giannetti, R. Bernini, G. Persichetti, G. Testa, G. Orellana, F. Salis, S. Weber, P. B. Luppa, G. Porro, G. Quarto, M. B. Schubert, M. Berner, P. J. Freitas, S. F. Cardoso, F. Franco, V. C. H. Silverio, M. J. Lopez-Martinez, U. Hilbig, K. Freudenberger, G. G. Gaüglitz, H. Becker, C. Gärtner, M. T. O’Connell, F. Baldini, An integrated device for fast and sensitive immunosuppressant detection, Analytical and Bioanalytical Chemistry (2022), 414 (10), 3243 - 3255, doi:10.1007/s00216-021-03847-x
T. K. Dey, S. Tombelli, P. Biswas, A. Giannetti, N. Basumallick, F. Baldini, S. Bandyopadhyay, C. Trono, Label-free immunosensing by long period fiber gratings at the lowest order cladding mode and near turn around point, Optics and Laser Technology (2021), 142 , doi:10.1016/j.optlastec.2021.107194
N. Cennamo, C. Trono*, A. Giannetti, F. Baldini, A. Minardo, L. Zeni, S. Tombelli, Biosensors exploiting unconventional platforms: The case of plasmonic light-diffusing fibers, Sensors and Actuators, B: Chemical (2021), 337 , doi:10.1016/j.snb.2021.129771
T. K. Dey, S. Tombelli, P. Biswas, A. Giannetti, N. Basumallick, F. Baldini, S. Bandyopadhyay, C. Trono, Analysis of the Lowest Order Cladding Mode of Long Period Fiber Gratings near Turn around Point, Journal of Lightwave Technology (2021), 39 (12), 4006 - 4012, doi:10.1109/JLT.2020.2987795
S. Weber, S. Tombelli, A. Giannetti, C. Trono, M. T. O'Connell, M. Wen, A. B. Descalzo, H. Bittersohl, A. Bietenbeck, P. Marquet, L. Renders, G. Orellana, F. Baldini, P. B. Luppa, Immunosuppressant quantification in intravenous microdialysate - Towards novel quasi-continuous therapeutic drug monitoring in transplanted patients, Clinical Chemistry and Laboratory Medicine (2021), 59 (5), 935 - 945, doi:10.1515/cclm-2020-1542
S. Berneschi, A. Barucci, F. Baldini, F. Cosi, F. Quercioli, S. Pelli, G. C. Righini, B. Tiribilli, S. Tombelli, C. Trono, A. Giannetti, Optical Fibre Micro/Nano Tips as Fluorescence-Based Sensors and Interrogation Probes, Optics (2020), 1 (2), 213 - 242, doi:10.3390/opt1020017
T. N. L. Tran, S. Berneschi, C. Trono, G. Nunzi Conti, L. Zur, C. Armellini, S. Varas, A. Carpentiero, A. Chiappini, A. P. Chiasera, J. C. Gates, P. J. A. Sazio, M. Bollani, A. Lukowiak, G. C. Righini, M. Ferrari, SiO2-SnO2:Er3+ planar waveguides: Highly photorefractive glass-ceramics, Optical Materials: X (2020), 7 , doi:10.1016/j.omx.2020.100056
A. Giannetti, C. Trono, G. Porro, C. Domenici, M. Puntoni, F. Baldini, Towards an integrated system as point-of-care device for the optical detection of sepsis biomarkers, Chemosensors (2020), 8 (1), doi:10.3390/chemosensors8010012
S. Berneschi, C. Trono*, M. Mirasoli, A. Giannetti, M. Zangheri, M. Guardigli, S. Tombelli, E. Marchegiani, F. Baldini, A. R. Roda, In-parallel polar monitoring of chemiluminescence emission anisotropy at the solid-liquid interface by an optical fiber radial array, Chemosensors (2020), 8 (1), doi:10.3390/chemosensors8010018
C. Trono*, F. Valeri, F. Baldini, Discretized superimposed optical fiber long-period gratings, Optics Letters (2020), 45 (4), 807 - 810, doi:10.1364/OL.382325
G. M. Giacomelli, S. Lepri, C. Trono, Optical networks as complex lasers, Physical Review A (2019), 99 (2), doi:10.1103/PhysRevA.99.023841
S. Berneschi, C. Trono*, R. Bernini, A. Giannetti, G. Persichetti, G. Testa, S. Tombelli, F. Baldini, A waveguide absorption filter for fluorescence measurements, Sensors and Actuators, B: Chemical (2019), 281 , 90 - 95, doi:10.1016/j.snb.2018.10.011
B. Adinolfi, M. Pellegrino, S. Tombelli, C. Trono, A. Giannetti, C. Domenici, G. Varchi, G. Sotgiu, M. Ballestri, F. Baldini, Polymeric nanoparticles promote endocytosis of a survivin molecular beacon: Localization and fate of nanoparticles and beacon in human A549 cells, Life Sciences (2018), 215 , 106 - 112, doi:10.1016/j.lfs.2018.11.007
F. Chiavaioli, P. Zubiate, I. Del Villar, C. R. Ruiz Zamarreño, A. Giannetti, S. Tombelli, C. Trono, F. J. Arregui, I. R. Matias, F. Baldini, Femtomolar Detection by Nanocoated Fiber Label-Free Biosensors, ACS Sensors (2018), 3 (5), 936 - 943, doi:10.1021/acssensors.7b00918
A Dessì, M. Monai, M. Bessi, T. Montini, M. Calamante, A. Mordini, G. Reginato, C. Trono, P. Fornasiero, L. Zani, Towards Sustainable H2 Production: Rational Design of Hydrophobic Triphenylamine-based Dyes for Sensitized Ethanol Photoreforming, ChemSusChem (2018), 11 (4), 793 - 805, doi:10.1002/cssc.201701707
S. Bandyopadhyay, P. Biswas, F. Chiavaioli, T. K. Dey, N. Basumallick, C. Trono, A. Giannetti, S. Tombelli, F. Baldini, S. Bandyopadhyay, Long-period fiber grating: A specific design for biosensing applications, Applied Optics (2017), 56 (35), 9846 - 9853, doi:10.1364/AO.56.009846
F. Chiavaioli, F. Baldini, C. Trono, Manufacturing and spectral features of different types of long period fiber gratings: Phase-shifted, turn-around point, internally tilted, and pseudo-random, Fibers (2017), 5 (3), doi:10.3390/fib5030029
S. Lepri, C. Trono, G. M. Giacomelli, Complex Active Optical Networks as a New Laser Concept, Physical Review Letters (2017), 118 (12), doi:10.1103/PhysRevLett.118.123901
A Lukowiak, L. Zur, T. N. L. Tran, M. Meneghetti, S. Berneschi, G. Nunzi Conti, S. Pelli, C. Trono, B. N. Shivakiran Bhaktha, D. Zonta, S. Taccheo, G. C. Righini, M. Ferrari, Sol–gel-derived glass-ceramic photorefractive films for photonic structures, Crystals (2017), 7 (2), doi:10.3390/cryst7020061
B. Adinolfi, M. Pellegrino, A. Giannetti, S. Tombelli, C. Trono, G. Sotgiu, G. Varchi, M. Ballestri, T. Posati, S. Carpi, P. Nieri, F. Baldini, Molecular beacon-decorated polymethylmethacrylate core-shell fluorescent nanoparticles for the detection of survivin mRNA in human cancer cells, Biosensors and Bioelectronics (2017), 88 , 15 - 24, doi:10.1016/j.bios.2016.05.102
P. Biswas, F. Chiavaioli, S. Jana, N. Basumallick, C. Trono, A. Giannetti, S. Tombelli, A. Mallick, F. Baldini, S. Bandyopadhyay, Design, fabrication and characterisation of silica-titania thin film coated over coupled long period fibre gratings: Towards bio-sensing applications, Sensors and Actuators, B: Chemical (2017), 253 , 418 - 427, doi:10.1016/j.snb.2017.06.139
F. Chiavaioli, F. Baldini, S. Tombelli, C. Trono, A. Giannetti, Biosensing with optical fiber gratings, Nanophotonics (2017), 6 (4), 663 - 679, doi:10.1515/nanoph-2016-0178
S. Berneschi, F. Baldini, A. Cosci, D. Farnesi, G. Nunzi Conti, S. Tombelli, C. Trono, S. Pelli, A. Giannetti, Fluorescence biosensing in selectively photo–activated microbubble resonators, Sensors and Actuators, B: Chemical (2017), 242 , 1057 - 1064, doi:10.1016/j.snb.2016.09.146
A Aray, F. Chiavaioli, M. Arjmand, C. Trono, S. Tombelli, A. Giannetti, N. Cennamo, M. Soltanolkotabi, L. Zeni, F. Baldini, SPR-based plastic optical fibre biosensor for the detection of C-reactive protein in serum, Journal of biophotonics (2016), 9 (10), 1077 - 1084, doi:10.1002/jbio.201500315
M. Arjmand, F. Chiavaioli, S. Berneschi, F. Baldini, M. Soltanolkotabi, C. Trono, Effect of induced inner curvature on refractive index sensitivity in internally tilted long-period gratings, Optics Letters (2016), 41 (7), 1443 - 1446, doi:10.1364/OL.41.001443
N. Cennamo, F. Chiavaioli, C. Trono, S. Tombelli, A. Giannetti, F. Baldini, L. Zeni, A complete optical sensor system based on a POF-SPR platform and a thermo-stabilized flow cell for biochemical applications, Sensors (Switzerland) (2016), 16 (2), doi:10.3390/s16020196
D. Ristić, S. Berneschi, M. Camerini, D. Farnesi, S. Pelli, C. Trono, A. Chiappini, A. P. Chiasera, M. Ferrari, A. Lukowiak, Y. Dumeige, P. Féron, G. C. Righini, S. Soria, G. Nunzi Conti, Photoluminescence and lasing in whispering gallery mode glass microspherical resonators, Journal of Luminescence (2016), 170 , 755 - 760, doi:10.1016/j.jlumin.2015.10.050
F. Chiavaioli, P. Biswas, C. Trono*, S. Jana, S. Bandyopadhyay, N. Basumallick, A. Giannetti, S. Tombelli, S. Bera, A. Mallick, F. Baldini, Sol-Gel-Based Titania-Silica Thin Film Overlay for Long Period Fiber Grating-Based Biosensors, Analytical Chemistry (2015), 87 (24), 12024 - 12031, doi:10.1021/acs.analchem.5b01841
D. Farnesi, F. Chiavaioli, F. Baldini, G. C. Righini, S. Soria, C. Trono, G. Nunzi Conti, Quasi-distributed and wavelength selective addressing of optical micro-resonators based on long period fiber gratings, Optics Express (2015), 23 (16), 21175 - 21180, doi:10.1364/OE.23.021175
G. Tuci, L. Luconi, A. Rossin, F. Baldini, S. Cicchi, S. Tombelli, C. Trono, A. Giannetti, I. Manet, S. Fedeli, A. Brandi, G. Giambastiani, A hetero-bifunctional spacer for the smart engineering of carbon-based nanostructures, ChemPlusChem (2015), 80 (4), 704 - 714, doi:10.1002/cplu.201402391
A Giannetti, A. Barucci, F. Cosi, S. Pelli, S. Tombelli, C. Trono, F. Baldini, Optical fiber nanotips coated with molecular beacons for DNA detection, Sensors (Switzerland) (2015), 15 (5), 9666 - 9680, doi:10.3390/s150509666
C. Berrettoni, C. Trono*, V. Vignoli, F. Baldini, Fibre tip sensor with embedded FBG-LPG for temperature and refractive index determination by means of the simple measurement of the FBG characteristics, Journal of Sensors (2015), 2015 , doi:10.1155/2015/491391
D. Farnesi, F. Chiavaioli, G. C. Righini, S. Soria, C. Trono, P. S. Jorge, G. Nunzi Conti, Long period grating-based fiber coupler to whispering gallery mode resonators, Optics Letters (2014), 39 (22), 6525 - 6528, doi:10.1364/OL.39.006525
D. Farnesi, F. Cosi, C. Trono, G. C. Righini, G. Nunzi Conti, S. Soria, Stimulated anti-Stokes Raman scattering resonantly enhanced in silica microspheres, Optics Letters (2014), 39 (20), 5993 - 5996, doi:10.1364/OL.39.005993
F. Chiavaioli, P. Biswas, C. Trono, S. Bandyopadhyay, A. Giannetti, S. Tombelli, N. Basumallick, K. Dasgupta, F. Baldini, Towards sensitive label-free immunosensing by means of turn-around point long period fiber gratings, Biosensors and Bioelectronics (2014), 60 , 305 - 310, doi:10.1016/j.bios.2014.04.042
F. Chiavaioli, C. Trono*, A. Giannetti, M. Brenci, F. Baldini, Characterisation of a label-free biosensor based on long period grating, Journal of Biophotonics (2014), 7 (5), 312 - 322, doi:10.1002/jbio.201200135
F. Chiavaioli, C. Trono, F. Baldini, Specially designed long period grating with internal geometric bending for enhanced refractive index sensitivity, Applied Physics Letters (2013), 102 (23), doi:10.1063/1.4810743
G. Ghini, C. Trono, A. Giannetti, G. L. Puleo, L. Luconi, J. Amadou, G. Giambastiani, F. Baldini, Carbon nanotubes modified with fluorescein derivatives for pH nanosensing, Sensors and Actuators, B: Chemical (2013), 179 , 163 - 169, doi:10.1016/j.snb.2012.10.022
S. Surdo, S. Merlo, F. M. Carpignano, L. M. Strambini, C. Trono, A. Giannetti, F. Baldini, G. Barillaro, Optofluidic microsystems with integrated vertical one-dimensional photonic crystals for chemical analysis, Lab on a Chip (2012), 12 (21), 4403 - 4415, doi:10.1039/c2lc40613f
P. P. Pilla, C. Trono, F. Baldini, F. Chiavaioli, M. Giordano, A. M. Cusano, Giant sensitivity of long period gratings in transition mode near the dispersion turning point: An integrated design approach, Optics Letters (2012), 37 (19), 4152 - 4154, doi:10.1364/OL.37.004152
G. Nunzi Conti, S. Berneschi, A. Barucci, F. Cosi, S. Soria, C. Trono, Fiber ring laser for intracavity sensing using a whispering-gallery-mode resonator, Optics Letters (2012), 37 (13), 2697 - 2699, doi:10.1364/OL.37.002697
F. Baldini, M. Brenci, F. Chiavaioli, A. Giannetti, C. Trono, Optical fibre gratings as tools for chemical and biochemical sensing, Analytical and Bioanalytical Chemistry (2012), 402 (1), 109 - 116, doi:10.1007/s00216-011-5492-3
C. Trono*, F. Baldini, M. Brenci, F. Chiavaioli, M. Mugnaini, Flow cell for strain- and temperature-compensated refractive index measurements by means of cascaded optical fibre long period and Bragg gratings, Measurement Science and Technology (2011), 22 (7), doi:10.1088/0957-0233/22/7/075204
E. Lubian, F. Baldini, A. Giannetti, C. Trono, T. Carofiglio, Solid-supported Zn(ii) porphyrin tweezers as optical sensors for diamines, Chemical Communications (2010), 46 (21), 3678 - 3680, doi:10.1039/c000954g
F. Baldini, A. Carloni, A. Giannetti, G. Porro, C. Trono, An optical PMMA biochip based on fluorescence anisotropy: Application to C-reactive protein assay, Sensors and Actuators, B: Chemical (2009), 139 (1), 64 - 68, doi:10.1016/j.snb.2008.08.027
F. Baldini, L. Bolzoni, A. Giannetti, M. Keß, P. M. Krämer, E. Kremmer, G. Porro, F. Senesi, C. Trono, A new procalcitonin optical immunosensor for POCT applications, Analytical and Bioanalytical Chemistry (2009), 393 (4), 1183 - 1190, doi:10.1007/s00216-008-2547-1
F. Baldini, A. Carloni, A. Giannetti, G. Porro, C. Trono, A new optical platform for biosensing based on fluorescence anisotropy, Analytical and Bioanalytical Chemistry (2008), 391 (5), 1837 - 1844, doi:10.1007/s00216-008-1904-4
F. Baldini, A. Giannetti, A. A. Mencaglia, C. Trono, Fiber optic sensors for biomedical applications, Current Analytical Chemistry (2008), 4 (4), 378 - 390, doi:10.2174/157341108785914880
N. Beverini, E. Maccioni, M. Morganti, F. Stefani, R. Falciai, C. Trono, Fiber laser strain sensor device, Journal of Optics A: Pure and Applied Optics (2007), 9 (10), 958 - 962, doi:10.1088/1464-4258/9/10/029
E. Maccioni, P. E. Bagnoli, N. Beverini, B. Bouhadef, E. Castorina, E. Falchini, R. Falciai, V. Flaminio, M. Morganti, F. Stefani, C. Trono, Fiber laser hydrophone as possible detector of UHE neutrinos, Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment (2007), 572 (1 SPEC. ISS.), 490 - 492, doi:10.1016/j.nima.2006.10.152
N. Beverini, R. Falciai, E. Maccioni, M. Morganti, F. Sorrentino, C. Trono, Developing fiber lasers with Bragg reflectors as deep sea hydrophones, Annals of Geophysics (2006), 49 (6), 1157 - 1165
P. E. Bagnoli, N. Beverini, B. Bouhadef, E. Castorina, E. Falchini, R. Falciai, V. Flaminio, E. Maccioni, M. Morganti, F. Sorrentino, F. Stefani, C. Trono, Erbium-doped fiber lasers as deep-sea hydrophones, Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment (2006), 567 (2), 515 - 517, doi:10.1016/j.nima.2006.05.177
P. E. Bagnoli, N. Beverini, E. Castorina, E. Falchini, R. Falciai, V. Flaminio, E. Maccioni, M. Morganti, F. Sorrentino, F. Stefani, C. Trono, Fiber laser hydrophones as pressure sensors, International Journal of Modern Physics A (2006), 21 (SUPPL. 1), 102 - 106, doi:10.1142/S0217751X06033441
P. E. Bagnoli, N. Beverini, R. Falciai, E. Maccioni, M. Morganti, F. Sorrentino, F. Stefani, C. Trono, Development of an erbium-doped fibre laser as a deep-sea hydrophone, Journal of Optics A: Pure and Applied Optics (2006), 8 (7), S535 - S539, doi:10.1088/1464-4258/8/7/S36
R. Falciai, C. Trono, Curved elastic beam with opposed fiber-bragg gratings for measurement of large displacements with temperature compensation, IEEE Sensors Journal (2005), 5 (6), 1310 - 1314, doi:10.1109/JSEN.2005.844344
R. Falciai, M. Morganti, C. Trono, Fibre Bragg grating location and spatial period determination in DBR lasers by side-scatter detection of pump radiation, Electronics Letters (2005), 41 (14), 792 - 794, doi:10.1049/el:20050946
R. Falciai, C. Trono, Simple tunable chirp of fiber Bragg gratings without center wavelength shift, Optical Engineering (2003), 42 (8), 2263 - 2267, doi:10.1117/1.1589525
R. Falciai, C. Trono, G. Lanterna, C. Castelli, Continuous monitoring of wooden works of art using fiber Bragg grating sensors, Journal of Cultural Heritage (2003), 4 (4), 285 - 290, doi:10.1016/j.culher.2003.01.001
Book Chapters
S. Berneschi, F. Baldini, D. Farnesi, G. Frigenti, A. Giannetti, S. Pelli, S. Soria, S. Tombelli, C. Trono, G. N. Conti, Inside the Wizard Sphere: Glass Microspheres and Their Application as Optical Source, Glass Photonics: Materials, Properties, and Applications (2026), 39 - 91, doi:10.1201/9781003748076-2
F. Baldini, A. Giannetti, C. Trono, Fundamentals of optical chemical sensors, Optochemical Nanosensors (2016), 35 - 50
F. Baldini, A. Giannetti, S. Tombelli, C. Trono, Optical biosensing in medical and clinical diagnostics, Photonics for Safety and Security (2013), 353 - 367, doi:10.1142/9789814412971_0016
